Short-Term Mortality Associated with Definitive Chemoradiotherapy Versus Radical Cystectomy for Muscle-Invasive Bladder Cancer

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[Bladder preservation by chemoradiotherapy in combination with radical TUR-Bt in muscle invasive bladder cancer].

PURPOSE To evaluate bladder preservation protocol by radical TUR-Bt and subsequent concurrent chemoradiotherapy in muscle invasive bladder cancer. PATIENTS AND METHODS Twenty-six patients with muscle invasive bladder cancer (T2-T4NOM0) were treated with concurrent chemoradiotherapy after transurethral resection of the tumor as much as possible beyond muscle layers. Chemotherapy was consisted ...

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Rethinking Radical Cystectomy as the Best Choice for Most Patients With Muscle-Invasive Bladder Cancer.

Should radical cystectomybeconsideredanalternative treatment to bladder preservation trimodality therapy in patients with muscle-invasive bladder cancer?—Yes. For the first time, the question is formulated correctly, and for the first time, based on new published evidence in 2015,1 bladder preservation trimodality therapy should be considered first for patients with muscle-invasive bladder canc...

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Radical Cystectomy is the best choice for most patients with muscle-invasive bladder cancer? Opinion: Yes

Around the World, radical cystectomy (RC) with bilateral pelvic lymphadenectomy (PLND) and perioperative chemotherapy is regarded as the standard treatment for patients with muscle-invasive bladder cancer (MIBC). This management approach is supported by numerous renowned organizations and guidelines, such as the National Comprehensive Cancer Network (NCCN), as well as by the European Associatio...

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Radical Cystectomy is the best choice for most patients with muscle-invasive bladder cancer? Opinion: No

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ژورنال

عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics

سال: 2019

ISSN: 0360-3016

DOI: 10.1016/j.ijrobp.2019.06.1946